Surely SEO includes the iStock 'search engine'? I'd be highly surprised if titles and descriptions didn't factor into search results.
They claim titles and descriptions (the latter of which don't even show on the file pages of non-editorial images, crazily) are for external search engines only and don't feature in their internal search. In my tiny-scale testing, only on my own files, I have found this to be the case. There have been a few people over the last couple of years who have suggested otherwise, but I haven't so far found their theories to be plausible. Not to say that isn't so.
However, there are some 'internal' CV mappings which are 'invisible' to us, both on uploading and subsequently, and some of them give 'surprising' results.